| AFC | Att | Yards | Avg | Long | TD |
|---|
| Terrell Davis, Den. | 392 | 2008 | 5.1 | 70 | 21 |
| Marshall Faulk, Ind. | 324 | 1319 | 4.1 | 68-td | 6 |
| Eddie George, Ten. | 348 | 1294 | 3.7 | 37-td | 5 |
| Curtis Martin, NYJ | 369 | 1287 | 3.5 | 60-td | 8 |
| Ricky Watters, Sea. | 319 | 1239 | 3.9 | 39-td | 9 |
| Fred Taylor*, Jax. | 264 | 1223 | 4.6 | 77-td | 14 |
| Jerome Bettis, Pit. | 316 | 1185 | 3.8 | 42 | 3 |
| Corey Dillon, Cin. | 262 | 1130 | 4.3 | 66 | 4 |
| Antowain Smith, Buf. | 300 | 1124 | 3.7 | 30 | 8 |
| Robert Edwards*, NE | 291 | 1115 | 3.8 | 53 | 9 |
| Priest Holmes, Bal. | 233 | 1008 | 4.3 | 56 | 7 |
| Karim Abdul-Jabbar, Mia. | 270 | 960 | 3.6 | 45 | 6 |
| Napoleon Kaufman, Oak. | 217 | 921 | 4.2 | 80-td | 2 |
| Natrone Means, SD | 212 | 883 | 4.2 | 72-td | 5 |
| Steve McNair, Ten. | 77 | 559 | 7.3 | 71-td | 4 |
| NFC | Att | Yards | Avg | Long | TD |
|---|
| Jamal Anderson, Atl. | 410 | 1846 | 4.5 | 48 | 14 |
| Garrison Hearst, SF | 310 | 1570 | 5.1 | 96-td | 7 |
| Barry Sanders, Det. | 343 | 1491 | 4.3 | 73-td | 4 |
| Emmitt Smith, Dal. | 319 | 1332 | 4.2 | 32 | 13 |
| Robert Smith, Min. | 249 | 1187 | 4.8 | 74-td | 6 |
| Duce Staley, Phi. | 258 | 1065 | 4.1 | 64-td | 5 |
| Gary Brown, NYG | 247 | 1063 | 4.3 | 45 | 5 |
| Adrian Murrell, Ari. | 274 | 1042 | 3.8 | 32 | 8 |
| Warrick Dunn, TB | 245 | 1026 | 4.2 | 50 | 2 |
| Mike Alstott, TB | 215 | 846 | 3.9 | 37 | 8 |
| Fred Lane, Car. | 205 | 717 | 3.5 | 31 | 5 |
| Terry Allen, Was. | 148 | 700 | 4.7 | 45 | 2 |
| Edgar Bennett, Chi. | 173 | 611 | 3.5 | 43 | 2 |
| Curtis Enis*, Chi. | 133 | 497 | 3.7 | 29 | 0 |
| Leroy Hoard, Min. | 115 | 479 | 4.2 | 50-td | 9 |
