| Batting—Bill Mueller, Boston | .326 |
| Home runs—Alex Rodriguez, Texas | 47 |
| Runs batted in—Carlos Delgado, Toronto | 145 |
| Runs—Alex Rodriguez, Texas | 124 |
| Hits—Vernon Wells, Toronto | 215 |
| Stolen bases—Carl Crawford, Tampa Bay | 55 |
| Doubles—Garret Anderson, Anaheim | 49 |
| Triples—Cristian Guzman, Minnesota | 14 |
| Slugging percentage—Alex Rodriguez, Texas | .600 |
A.L. Pitching
| Wins—Roy Halladay, Toronto | 22 |
| Earned run average—Pedro Martinez, Boston | 2.22 |
| Strikeouts—Esteban Loaiza, Chicago | 207 |
| Innings pitched—Roy Halladay, Toronto | 266 |
| Complete games—Bartolo Colon, Chicago | 9 |
| Shutouts—Roy Halladay, Toronto | 2 |
| Saves—Keith Foulke, Oakland | 43 |
